Mouse Anti-Sheep TOP3A Antibody (MO-AB-18037Y)
Cat: MO-AB-18037Y
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Sheep (Ovis aries) |
| Clone | MO18037Y |
| Specificity | This antibody binds to Sheep TOP3A. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations; Mitochondrion |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. |
| Product Overview | This product is a mouse antibody against TOP3A. It can be used for TOP3A detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | DNA topoisomerase; EC 5.99.1.2; TOP3A |
| UniProt ID | W5NPJ3 |
| Protein Refseq | The length of the protein is 1021 amino acids long. The sequence is show below: MIFPALRRALRGLPRPGARALTRAAMEVALRGVRKILCVAEKNDAAKGIADLLSGGRMRRREGLSRFNKIYEFDYHLCGQNVTMVMTSVSGHLLAHDFRMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLEREARQCQALVIWTDCDREGENIGFEVIHVCKAVKPSLQVLRARFSEITARAVRTACENLTEPDQRVSDAVDVRQELDLRIGEEGAVRVGGQGSGAHPAVTLPSAVSPSVPPLCQGREVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIRVTHDHRDGVVEFSWKRHRLFNHTACLVLYQLCMEDPRATVVEVRSKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLDLAALVEQQIPDPRWGAFARNILERGGPTPRNGNKSDQAHPPIHPTKYTDSLQGDEQRLYELIVRHFLACCSQDAQGQETTVEIDIVQERFVAHGLMILARNYLDVYPYDRWSDKTLPVYKEGTYFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKLVVLHQQVQKYKQVFIEAVAKARKLDEALSQYFGAAAEVAPQEALPAVSEPIRKCPQCGRDMVLKTRKSGGFYLSCTGFPECRSAVWFPDSVLEASRDASVCPVCQPRPIYRLKFKFKRGSLPPTMPLEFVGCIGGCDETLREILALRFSQGAPRVGQPASQTSGYLQASQSLNRMDSGQQGQPRPPVTRPSKALTRTLPPPAVESESNSVTCNCGREALLLTVRKEGPNQGRQFYKCSGGGCSFFLWADSGHPGAEPPSSASRPPGGPLGRPPGSGTLLGGSSRSGSAGSAGTSCLCGQPAVTRTVQKEGPNQGRQFHTCAQPREQQCGFFQWVDENVAPGTLGGPLWPGSKGGTQGLEARSKRARANSSDTGSAAKKPRKCSLCHQPGHTRPFCPQNR. |
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| MO-AB-42725W | Mouse Anti-Guinea pig TOP3A Antibody (MO-AB-42725W) |
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| CBMOAB-10378FYB | Mouse Anti-Zebrafish top3a Antibody (CBMOAB-10378FYB) |
For Research Use Only | Not For Clinical Use.
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