Rabbit Anti-GAD2 Antibody (MO-DKB-00628W)
Cat: MO-DKB-00628W
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- Product Details
Specifications
Host species | Rabbit (Oryctolagus cuniculus) |
Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Bovine (Bos taurus), Dog (Canis lupus familiaris), Rhesus (Macaca mulatta) |
Immunogen | A recombinant protein containing the sequence in the C-terminal region of human GAD65. |
Epitope | The epitope is in the C-terminal of GAD2. |
Format | Liquid or Lyophilized |
Buffer | PBS, pH7, 20% Glycerol |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | Affinity purified |
Cellular Localization | Cytoplasm, cytosol, Cytoplasmic vesicle, Cell junction, synapse, presynaptic cell membrane, Golgi apparatus membrane |
Application Information
Application | WB, IF, IHC, IHC-P |
Application Notes | Western Blot 1:500-1:3000 Immunocytochemistry/Immunofluorescence 1:100-1:1000 Immunohistochemistry 1:100-1:1000 Immunohistochemistry-Paraffin 1:100-1:1000 |
Target
Introduction | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008] |
Product Overview | This product is a Rabbit antibody against the C-terminal of the GAD2. It can be used for GAD2 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin. |
Alternative Names | Glutamate Decarboxylase 2; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 5 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65; |
Gene ID | 2572 |
UniProt ID | Q05329 |
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For Research Use Only | Not For Clinical Use.
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