Rabbit Anti-GLE1 Antibody (MO-DKB-02142W)


Cat: MO-DKB-02142W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
ImmunogenGLE1 synthetic peptide derived from Arabidopsis AT1G13120.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityPeptide affinity purified

Application Information

ApplicationWB
Application NotesWestern Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user.

Target

IntroductionThis gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product OverviewThis product is a Rabbit antibody against the GLE1. It can be used for GLE1 detection in Western Blot.
Alternative NamesGLE1, RNA Export Mediator; GLE1-Like Protein; GLE1L; HGLE1; GLE1 (Yeast Homolog)-Like, RNA Export Mediator; Lethal Congenital Contracture Syndrome 1; GLE1 RNA Export Mediator Homolog (Yeast); GLE1 RNA Export Mediator-Like (Yeast); GLE1, A. THALIANA HOMOLOG OF YEAST GLE1, ATGLE1
UniProt IDQ0WPZ7
For Research Use Only | Not For Clinical Use.
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