AibGenesis™ Mouse Anti-GLIS2 Antibody (CBMOAB-43665FYA)


Cat: CBMOAB-43665FYA

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Lot Number

  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-43665FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset WB, ELISA MO43665FYA 100 µg
MO-AB-13110R Monoclonal Cattle (Bos taurus) WB, ELISA MO13110R 100 µg
MO-AB-18693W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO18693W 100 µg
MO-AB-56058W Monoclonal Marmoset WB, ELISA MO56058W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset
CloneMO43665FYA
SpecificityThis antibody binds to Rhesus GLIS2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys. (From NCBI)
Product OverviewMouse Anti-Rhesus GLIS2 Antibody is a mouse antibody against GLIS2. It can be used for GLIS2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGLIS2
UniProt IDF6RYU5
Protein RefseqThe length of the protein is 522 amino acids long.
The sequence is show below: MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSAMVIGRMAKCVHQHVAAAPLGFQLTGSPQPYLEELVGQPGIQKVWQRSQELHPGPHAQDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKSGKSFSRLENLKIHNRSHTGKRPGPGSSAHEGAGVNQPGFSESLCALPGARSHATCRGCPLPPELGRRGETPHSSTALHHPAGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPFVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGRKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN.
For Research Use Only | Not For Clinical Use.
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