Mouse Anti-GP5 Antibody (CBMOAB-43847FYA)


Cat: CBMOAB-43847FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-43847FYA Monoclonal Rhesus (Macaca mulatta), Frog (Xenopus laevis) WB, ELISA MO43847FYA 100 µg
MO-AB-03996H Monoclonal Frog (Xenopus laevis) WB, ELISA MO03996C 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Frog (Xenopus laevis)
CloneMO43847FYA
SpecificityThis antibody binds to Rhesus GP5.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionHuman platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).
Product OverviewMouse Anti-Rhesus GP5 Antibody is a mouse antibody against GP5. It can be used for GP5 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGP5
UniProt IDF6X4B0
Protein RefseqThe length of the protein is 561 amino acids long.
The sequence is show below: MLRRTLLCAVLGLLRAQPFPCPPACKCVFRDAAQCSAGDVARIAALGLPTNLTHILLFGMGRGVLQNQSFSGMTVLQRLMLSDSHISAVAPGAFNDLVKLKTLRLSRNKITHLPGALLDKTVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPAGLFTNLGNLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSELLNSLGALTELQLHRNHIRCITPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHSLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPVAAFRNLSRLRSLGVTLSPRLSALPQGAFQGLGELRVLSLHSNGLTALPDGLLRGLGRLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDAFGALPRLKEVLLGHNPWRCDCGLGPFLGWLRQHPGLAGLEEPPRCAGPGKLAGLPLWALPGGDAECPGPRGPPPHPAADSSSDSSPVHPALAPNSSEPWMWAQPVATGEYQDHGPFWGFYFLLLAVQALITVIIVLAMIKIGQLFRKLIRERALR.
For Research Use Only | Not For Clinical Use.
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