Mouse Anti-GP5 Antibody (CBMOAB-43847FYA)
Cat: CBMOAB-43847FYA
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- Product List
- Specifications
- Application Information
- Target
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta), Frog (Xenopus laevis) |
Clone | MO43847FYA |
Specificity | This antibody binds to Rhesus GP5. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]). |
Product Overview | Mouse Anti-Rhesus GP5 Antibody is a mouse antibody against GP5. It can be used for GP5 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | GP5 |
UniProt ID | F6X4B0 |
Protein Refseq | The length of the protein is 561 amino acids long. The sequence is show below: MLRRTLLCAVLGLLRAQPFPCPPACKCVFRDAAQCSAGDVARIAALGLPTNLTHILLFGMGRGVLQNQSFSGMTVLQRLMLSDSHISAVAPGAFNDLVKLKTLRLSRNKITHLPGALLDKTVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPAGLFTNLGNLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSELLNSLGALTELQLHRNHIRCITPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHSLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPVAAFRNLSRLRSLGVTLSPRLSALPQGAFQGLGELRVLSLHSNGLTALPDGLLRGLGRLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDAFGALPRLKEVLLGHNPWRCDCGLGPFLGWLRQHPGLAGLEEPPRCAGPGKLAGLPLWALPGGDAECPGPRGPPPHPAADSSSDSSPVHPALAPNSSEPWMWAQPVATGEYQDHGPFWGFYFLLLAVQALITVIIVLAMIKIGQLFRKLIRERALR. |
For Research Use Only | Not For Clinical Use.
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