Rabbit Anti-GPX1 Antibody (MO-DKB-01996W)
Cat: MO-DKB-01996W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | A. thaliana (Arabidopsis thaliana) |
| Immunogen | GPX1 synthetic peptide derived from Arabidopsis AT2G25080. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Peptide affinity purified |
Application Information
| Application | WB |
| Application Notes | Western Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. This gene contains an in-frame GCG trinucleotide repeat in the coding region, and three alleles with 4, 5 or 6 repeats have been found in the human population. The allele with 4 GCG repeats has been significantly associated with breast cancer risk in premenopausal women. Alternatively spliced transcript variants have been found for this gene. Pseudogenes of this locus have been identified on chromosomes X and 21. |
| Product Overview | This product is a Rabbit antibody against the GPX1. It can be used for GPX1 detection in Western Blot. |
| Alternative Names | Glutathione Peroxidase 1; Cellular Glutathione Peroxidase; EC 1.11.1.9; GSHPx-1; EC 1.11.1; GSHPX1; GPx-1; GPXD; GPX1, ATGPX1, GLUTATHIONE PEROXIDASE 1, GPXL1. |
| UniProt ID | P52032 |
See other products for " GPX1 "
| MO-AB-08258Y | Mouse Anti-Rabbit GPX1 Antibody (MO-AB-08258Y) |
| MO-AB-08785W | Mouse Anti-Cat GPX1 Antibody (MO-AB-08785W) |
| MO-AB-00625R | Mouse Anti-Medaka gpx1 Antibody (MO-AB-00625R) |
| MO-DKB-00593W | Rabbit Anti-GPX1 Antibody (MO-DKB-00593W) |
| MO-AB-26099H | Mouse Anti-Rat Gpx1 Antibody (MO-AB-26099H) |
| MO-AB-13331R | Mouse Anti-Cattle GPX1 Antibody (MO-AB-13331R) |
| CBMOAB-01572CR | Mouse Anti-Yeast GPX1 Antibody (CBMOAB-01572CR) |
| CBMOAB-04654HCB | Mouse Anti-C. elegans GPX1 Antibody (CBMOAB-04654HCB) |
| MO-AB-02214Y | Mouse Anti-Chicken GPX1 Antibody (MO-AB-02214Y) |
| MO-AB-31013W | Mouse Anti-Dog GPX1 Antibody (MO-AB-31013W) |
For Research Use Only | Not For Clinical Use.
Online Inquiry