AibGenesis™ Mouse Anti-GRAMD1C Antibody (CBMOAB-44084FYA)
Cat: CBMOAB-44084FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-44084FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Frog (Xenopus laevis) | WB, ELISA | MO44084FYA | 100 µg | ||
| MO-AB-03741W | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO03741W | 100 µg | ||
| MO-AB-04050H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO04050C | 100 µg | ||
| MO-AB-13340R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO13340R | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Frog (Xenopus laevis) |
| Clone | MO44084FYA |
| Specificity | This antibody binds to Rhesus GRAMD1C. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER. Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol. In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain. At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER. (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Rhesus GRAMD1C Antibody is a mouse antibody against GRAMD1C. It can be used for GRAMD1C detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | GRAMD1C |
| UniProt ID | F6TRE0 |
| Protein Refseq | The length of the protein is 531 amino acids long. The sequence is show below: MTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLSRQEFRQLLQQNYGPELGFSAEEMENLSLSIEDVQPRSPGRSSLDDSGERDEKLSKSISFTSESISRVSETELFDGNSSKGGLGKEESQNEKQTKKSLLPALEKKLTRVPSKSLDLNKNEYLSLDKSSTSDSVDEENVSEKDLHGRLFINRVFHISADRMFELLFTSSRFMQKFASSRNIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTGKCTTATEKQTLYKESQEARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDVKYRKQPWGLVKSLIEKNSWSSLEDYFKQLESDLLIEESILNQAIEDPGKLTGLRRRRRAFNRTAETVPKLSSQHSSGHVGLGAKGDITGKKKDMENYNVTLIVVMSIFVVLLVLLNVTLFLKLSKIEHAAQSFYRLRLQEEKSLNLASHMVSRAENIQKNKDQAHRLKGVLRDSIVMLEQLKSSLIMLQKTFDLLNKNKTGMAVES. |
For Research Use Only | Not For Clinical Use.
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