AibGenesis™ Mouse Anti-GRX1 Antibody (CBMOAB-01582CR)


Cat: CBMOAB-01582CR

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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-01582CR Monoclonal Yeast, Cucumber (Cucumis sativus), Fruit fly (Drosophila melanogaster), Pig (Sus scrofa) WB, ELISA MO01582CR 100 µg
MO-AB-02656W Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO02656W 100 µg
MO-AB-26237R Monoclonal Pig (Sus scrofa) WB, ELISA MO26237R 100 µg
MO-AB-28471W Monoclonal Cucumber (Cucumis sativus) WB, ELISA MO28471W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast, Cucumber (Cucumis sativus), Fruit fly (Drosophila melanogaster), Pig (Sus scrofa)
CloneMO01582CR
SpecificityThis antibody binds to Yeast GRX1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of the glutathione system which performs several activities such as glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity (PubMed:11875065, PubMed:12684511). The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. GRX1 is less active as an oxidoreductase than GRX2 (PubMed:9571241, PubMed:18992757, PubMed:20417731). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-Yeast GRX1 Antibody is a mouse antibody against GRX1. It can be used for GRX1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGlutaredoxin-1; Glutathione-dependent oxidoreductase 1; GRX1; YCL035C
UniProt IDP25373
Protein RefseqThe length of the protein is 110 amino acids long. The sequence is show below: MVSQETIKHVKDLIAENEIFVASKTYCPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDDLQELRETGELEELLEPILAN.
For Research Use Only | Not For Clinical Use.
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