Mouse Anti-Guinea pig APP Antibody (MO-AB-41259W)


Cat: MO-AB-41259W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityGuinea pig (Cavia porcellus)
CloneMO41259W
SpecificityThis antibody binds to Guinea pig APP.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Extracellular region or secreted; Golgi apparatus; Endosome; Nucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Product OverviewMouse Anti-Guinea pig APP Antibody is a mouse antibody against APP. It can be used for APP detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAmyloid beta A4 protein; ABPP; APP; Alzheimer disease amyloid A4 protein homolog; [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); CTF-alpha; CTF-beta; Beta-amyloid protein 42 (Beta-APP42)
UniProt IDQ60495
Protein RefseqThe length of the protein is770 amino acids long.
The sequence is show below: MLPSLALLLLTTWTARALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWEPDPSGTKTCIGSKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNIDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVADVEEEEADDDEDVEDGDEVEEEAEEPYEEATEKTTSIATTTTTTTESVEEVVREVCSEQAETGPCRSMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQNLLKTSGEPVSQGPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN.
See other products for " App "
CBMOAB-01114FYAMouse Anti-D. melanogaster App Antibody (CBMOAB-01114FYA)
MO-AB-42938WMouse Anti-Hamsters APP Antibody (MO-AB-42938W)
MO-AB-00093LMouse Anti-Elephant APP Antibody (MO-AB-00093L)
MO-AB-14223YMouse Anti-Sheep APP Antibody (MO-AB-14223Y)
MO-AB-01500HMouse Anti-Frog app Antibody (MO-AB-01500H)
MO-AB-00073HMouse Anti-Arabidopsis APP Antibody (MO-AB-00073H)
MO-AB-00156YMouse Anti-Chicken APP Antibody (MO-AB-00156Y)
MO-AB-08377WMouse Anti-Cat APP Antibody (MO-AB-08377W)
MO-DKB-00490WRabbit Anti-APP Antibody (MO-DKB-00490W)
MO-AB-01096WMouse Anti-Rhesus APP Antibody (MO-AB-01096W)
For Research Use Only | Not For Clinical Use.
Online Inquiry