Mouse Anti-Guinea pig Cbs Antibody (MO-AB-41350W)
Cat: MO-AB-41350W
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Guinea pig (Cavia porcellus) |
| Clone | MO41350W |
| Specificity | This antibody binds to Guinea pig Cbs. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. |
| Product Overview | Mouse Anti-Guinea pig Cbs Antibody is a mouse antibody against Cbs. It can be used for Cbs detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Cystathionine beta-synthase; EC 4.2.1.22; Cbs |
| UniProt ID | H0VAY2 |
| Protein Refseq | The length of the protein is538 amino acids long. The sequence is show below: MPLETPQVEIGAAACPYLSGVPEGDKERLWIPPDTPSRCTWHLGRPVTDSPHRHAHLAESPKILPDILSNIGNTPLIRINKIGKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAELDGTLKPGATIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLTHYDTTAEEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPKCRIIGVDPEGSILAEPEELNRKEKTTYEVEGIGYDFIPTVLDRAVVDEWFKSNDEESFAFARMLIAQEGLLCGGSSGSVMAVAVKAAQELQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFLKEEVLSVKKPWWWHRRVQELSLSAPLTVLPTITCGHTIAILREKGFDQAPVVDESGAILGMVTLGNMLSSLLAGKVRPADQVCKVLYRQFRPVHLTDTLGMLSHILETDHFALVVHKQIQYHINGEANARQMVFGVVTAIDLLNFVATHEKDQK. |
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For Research Use Only | Not For Clinical Use.
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