Mouse Anti-Cattle CBS Antibody (MO-AB-09579R)
Cat: MO-AB-09579R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO09579R |
Specificity | This antibody binds to Cattle CBS. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016] |
Product Overview | Mouse Anti-Cattle CBS Antibody is a mouse antibody against CBS. It can be used for CBS detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Cystathionine beta-synthase; EC 4.2.1.22; CBS |
UniProt ID | A7MBF8 |
Protein Refseq | The length of the protein is 571 amino acids long. The sequence is show below: MPFETSPADTLCRSAGCPHLSGAHLGRGSLEKEPPEDKEAKELLWIRPDAPSRCSWQLGRPVADSPHCHAALVKSPKILPDILKKIGDTPMVRINKIGRNFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAEREGTIKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSTEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLRNEIPNSHILDQYRNASNPLAHYDITAEEILQQCDGRLDMLVA. |
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For Research Use Only | Not For Clinical Use.
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