Rabbit Anti-CBS (N-terminal) Antibody (Cat MO-DKB-03339W)


Cat: MO-DKB-03339W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Horse (Equus caballus), Guinea pig (Cavia porcellus), Rabbit (Oryctolagus cuniculus), Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Human CBS and has cross reactivity with Mouse, Rat, Cattle, Dog, Horse, Guinea pig, Rabbit, Zebrafish CBS.
ImmunogenThe synthetic peptide peptide sequence corresponding to CBS (cystathionine-β-synthase) is selected from the N-terminus of CBS. Peptide sequence RCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNE. The peptide sequence of the immunogen was taken from the region.
EpitopeN-terminal
FormatLiquid or Lyophilized
BufferPBS, 2% Sucrose
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A purified

Application Information

ApplicationWB, IHC, IHC-P
Application NotesWestern Blot: 1.0 ug/mL
Immunohistochemistry: 1:10-1:500
Immunohistochemistry-Paraffin: 1:10-1:500
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Product OverviewThis product is a Rabbit antibody against the CBS. It can be used for CBS detection in Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesCystathionine-Beta-Synthase; Serine Sulfhydrase; Beta-Thionase; EC 4.2.1.22; Cystathionine Beta-Synthase; Methylcysteine Synthase; HIP4;
Gene ID875
UniProt IDP35520
For Research Use Only | Not For Clinical Use.
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