Mouse Anti-Rhesus CBS Antibody (MO-AB-03469W)


Cat: MO-AB-03469W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO03469W
SpecificityThis antibody binds to Rhesus CBS.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.
Product OverviewMouse Anti-Rhesus CBS Antibody is a mouse antibody against CBS. It can be used for CBS detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCystathionine-Beta-Synthase; Serine Sulfhydrase; Beta-Thionase; EC 4.2.1.22; Cystathionine Beta-Synthase; Methylcysteine Synthase; HIP4
UniProt IDF7H3T2
Protein RefseqThe length of the protein is 525 amino acids long.
The sequence is show below: MPSETPQAEVGPTGCPHLSGPHSAQGSLEKGLPGDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTVPEKSPKILPDILKKIGDTPMIRINKIGKKFGLKCELLAKCEFFNAGGSPASGCAPMSQAGVGRDLEGHRAPLILSVPSGIGLALTAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILRQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTMAVAVKAAQELQEGQRCVVILPDSVRNYIPAALVARALLPRGYTAPESSAALGGPRPGWWHERTCFDGCVHAHTCSHTLVGHGGQKVQPTGFPLGPLASTWGVILGMVTLGNMLSSMLAGKVQPSDQVGKVIYTQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQR.
For Research Use Only | Not For Clinical Use.
Online Inquiry