Mouse Anti-H2AV Antibody (MO-AB-11572Y)
Cat: MO-AB-11572Y
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- Product List
- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | O. mykiss (Oncorhynchus mykiss), A. thaliana (Arabidopsis thaliana) |
| Clone | MO11572Y |
| Specificity | This antibody binds to O. mykiss H2AV. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Other locations; Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The nucleosome is the smallest subunit of chromatin and consists of 147 DNA base pairs wrapped around the core histone octamer (histone H2A, histone H2B, histone H3, and histone H4). Histone H2A.Z (H2AZ, H2AFZ) is a variant of histone H2A, a protein similar to classic H2A, but with a different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatin silencing, and cell cycle progression. In Drosophila, the H2A variant corresponding to H2AZ is H2Av. H2Av is an essential protein in Drosophila and is involved in the activation and inhibition of transcription. H2Av is located in the centromeric heterochromatin in Drosophila, and the level of heterochromatin in the centromere of Drosophila lacking H2Av is reduced. However, the distribution of H2Av nucleosomes throughout the rest of the Drosophila genome is related to genes with an open and uniform chromatin structure in the promoter region. |
| Product Overview | This product is a mouse antibody against H2AV. It can be used for H2AV detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Histone H2A; H2AV |
| UniProt ID | C1BFL4 |
| Protein Refseq | The length of the protein is 128 amino acids long. The sequence is show below: MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA. |
See other products for " H2Av "
For Research Use Only | Not For Clinical Use.
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