Anti-H3K56ac Antibody (Cat MO-MMB-0704), Mouse IgG1


Cat: MO-MMB-0704
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-MMB-0704 Monoclonal Budding Yeast, Fission Yeast, Human (Homo sapiens) ChIP, DB MMB4 100 µg
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MO-MMB-0705 Polyclonal Budding Yeast, Human (Homo sapiens) ChIP, ChIP-Seq, WB, DB 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityBudding Yeast, Fission Yeast, Human (Homo sapiens)
CloneMMB4
ImmunogenThis Histone H3 acetyl Lys56 antibody is raised against the acetyl-Lys56 peptide containing human histone H3.
FormatLiquid or Lyophilized
Buffer70 mM Tris, pH 8, 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein G purified

Application Information

ApplicationChIP, DB
Application NotesChIP: 2-10 µg per ChIP
DB: 1 µg/mL
The optimal dilution should be determined by the end user.

Target

IntroductionHistone H3 is one of the core components of nucleosomes. The nucleosome is the smallest subunit of chromatin and consists of 147 DNA base pairs wrapped around the core histone octamer (histone H2A, histone H2B, histone H3, and histone H4). Histone H1 is a linker histone that exists at the interface between the nucleosome core and the DNA entry/exit point; it is responsible for building higher-order chromatin structures. Chromatin undergoes a variety of chemical modifications, including post-translational modifications of histones and methylation of cytosine residues in DNA. The reported histone modifications include acetylation, methylation, phosphorylation, ubiquitination, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; they play a major role in regulating gene expression.
Alternative NamesH3K56ac; Histone H3K56ac
For Research Use Only | Not For Clinical Use.
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