Cat: MO-MMB-0704
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Budding Yeast, Fission Yeast, Human (Homo sapiens) |
| Clone | MMB4 |
| Immunogen | This Histone H3 acetyl Lys56 antibody is raised against the acetyl-Lys56 peptide containing human histone H3. |
| Format | Liquid |
| Buffer | 70 mM Tris, pH 8, 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Purification | Protein G purified |
Application Information
| Application | ChIP, DB |
| Application Notes | ChIP: 2-10 µg per ChIP DB: 1 µg/mL The optimal dilution should be determined by the end user. |
Target
| Introduction | Histone H3 is one of the core components of nucleosomes. The nucleosome is the smallest subunit of chromatin and consists of 147 DNA base pairs wrapped around the core histone octamer (histone H2A, histone H2B, histone H3, and histone H4). Histone H1 is a linker histone that exists at the interface between the nucleosome core and the DNA entry/exit point; it is responsible for building higher-order chromatin structures. Chromatin undergoes a variety of chemical modifications, including post-translational modifications of histones and methylation of cytosine residues in DNA. The reported histone modifications include acetylation, methylation, phosphorylation, ubiquitination, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; they play a major role in regulating gene expression. |
| Alternative Names | H3K56ac; Histone H3K56ac |
Reference
See other products for " H3K56ac "
For Research Use Only | Not For Clinical Use.