Anti-H4K12ac Antibody (Cat MO-MMB-0706), Rabbit IgG


Cat: MO-MMB-0706
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-MMB-0706 Polyclonal Budding Yeast, Human (Homo sapiens), Mouse (Mus musculus) ChIP, ChIP-Seq, WB, IF 100 µg
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MO-MMB-0707 Polyclonal Budding Yeast, Human (Homo sapiens), Mouse (Mus musculus) ChIP-Seq, IF 100 µg
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityBudding Yeast, Human (Homo sapiens), Mouse (Mus musculus)
ImmunogenThe Histone H4 acetyl Lys12 antibody is raised against a peptide, including the acetyl lysine 12 of histone H4.
FormatLiquid or Lyophilized
Buffer30% Glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationChIP, ChIP-Seq, WB, IF
Application NotesChIP: 2-8 µL per ChIP
ChIP-Seq: 5 µL each
IF: 1:500-1:2000
WB: 1:5000-1:20000
The optimal dilution should be determined by the end user.

Target

IntroductionHistone H4 is one of the core components of nucleosomes. The nucleosome is the smallest subunit of chromatin and consists of 147 DNA base pairs wrapped around the core histone octamer (histone H2A, histone H2B, histone H3, and histone H4). Histone H1 is a linking histone that exists at the interface between the nucleosome core and DNA entry/exit points; it is responsible for building higher-order chromatin structures. Chromatin undergoes a variety of chemical modifications, including post-translational modifications of histones and methylation of cytosine residues in DNA. The reported histone modifications include acetylation, methylation, phosphorylation, ubiquitination, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; they play a major role in regulating gene expression.
Alternative NamesH4K12ac; Histone H4K12ac
For Research Use Only | Not For Clinical Use.
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