Rabbit Anti-HDA6 (C-terminal) Antibody (Cat MO-DKB-04047W)

Cat: MO-DKB-04047W
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Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
SpecificityThis antibody is binds to A. thaliana HDA6.
ImmunogenA GST-fusion protein containing the C-terminal region of arabidopsis thaliana HDA6 (AT5G63110).
FormatLiquid or Lyophilized
BufferPBS, pH 7.4, 100 ug/mL BSA, 40% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified

Application Information

Application NotesWestern Blot: 1:500-1:2000
The optimal dilution should be determined by the end user.


IntroductionHDA6 is responsible for the deacetylation of the N-terminal lysine residues of the core histones (H2A, H2B, H3, and H4). HDA6 may only remove acetyl residues from specific targets, such as rDNA repetitive sequences or complex transgenes. Histone deacetylation provides a label for epigenetic suppression and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Histone deacetylase works by forming large multiprotein complexes. HDA6 is required for rRNA gene silencing in nucleolar dominance. HDA6 plays a role in transgene silencing, but this effect does not seem to be related to histone deacetylase activity.
Product OverviewThis product is a Rabbit antibody against the HDA6. It can be used for HDA6 detection in Western Blot.
Alternative NamesHistone deacetylase; EC; HDA6; At5g63110; Histone deacetylase 6; RPD3B; At5g63110; MDC12.7
UniProt IDQ9FML2
For Research Use Only | Not For Clinical Use.
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