Rabbit Anti-HDAC4 Antibody (MO-DKB-00511W)


Cat: MO-DKB-00511W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Fruit fly (Drosophila melanogaster)
ImmunogenSynthesized non-phosphopeptide derived from human HDAC4/HDAC5/HDAC9 around amino acids 244~248/257~261/218~222.
FormatLiquid or Lyophilized
BufferPBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified

Application Information

ApplicationWB, IF, IHC, IHC-P
Application NotesWestern Blot 1:500-1:1000
Immunocytochemistry/Immunofluorescence 1:10-1:500

Target

IntroductionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
Product OverviewThis product is a Rabbit antibody against the HDAC4. It can be used for HDAC4 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesHistone Deacetylase 4; EC 3.5.1.98; HD4; Brachydactyly-Mental Retardation Syndrome; Histone Deacetylase A; KIAA0288; HA6116;
Gene ID9759
UniProt IDP56524
For Research Use Only | Not For Clinical Use.
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