Mouse Anti-HLA-A Antibody (CBMOAB-44601FYA)
Cat: CBMOAB-44601FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-44601FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis) | WB, ELISA | MO44601FYA | 100 µg | ||
| MO-AB-04260H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO04260C | 100 µg | ||
| MO-AB-13685R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO13685R | 100 µg | ||
| MO-AB-14322W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO14322W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis) |
| Clone | MO44601FYA |
| Specificity | This antibody binds to Rhesus HLA-A. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. |
| Product Overview | Mouse Anti-Rhesus HLA-A Antibody is a mouse antibody against HLA-A. It can be used for HLA-A detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | HLA class I histocompatibility antigen, A-1 alpha chain; HLA-A |
| UniProt ID | H9FAU2 |
| Protein Refseq | The length of the protein is 26 amino acids long. The sequence is show below: KGGSYSQAASNDSAQGSDVSLTACKV. |
For Research Use Only | Not For Clinical Use.
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