AibGenesis™ Mouse Anti-HMG3 Antibody (CBMOAB-05014HCB)
Cat: CBMOAB-05014HCB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-05014HCB | Monoclonal | C. elegans (Caenorhabditis elegans), Maize (Zea mays), Rice (Oryza) | WB, ELISA | MO05014HB | 100 µg | ||
| CBMOAB-23139FYB | Monoclonal | Rice (Oryza) | WB, ELISA | MO23139FYB | 100 µg | ||
| MO-AB-48400W | Monoclonal | Maize (Zea mays) | WB, ELISA | MO48400W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans), Maize (Zea mays), Rice (Oryza) |
| Clone | MO05014HB |
| Specificity | This antibody binds to C. elegans HMG3. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to double-stranded DNA. In embryos, may function redundantly with hmg-4 to promote cell cycle progression and development of the anterior pharynx (PubMed:30336114). In the germline, acts non-redundantly with hmg-4 to play a role in oocyte development (PubMed:30336114). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-C. elegans HMG3 Antibody is a mouse antibody against HMG3. It can be used for HMG3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | FACT complex subunit ssrp1-B; Facilitates chromatin transcription complex subunit ssrp1-B; HMG box-containing protein 3; Structure-specific recognition protein 1-B; hmg-3 |
| UniProt ID | O01683 |
| Protein Refseq | The length of the protein is 689 amino acids long. The sequence is show below: MTELKFKGVYVEDIGHLTCGTLTLTENSINFIGDKGGKSVYITGTDVDKLKWQKLGNKPGLRVGLSDGGAHRFGGFLDDDLQKIQSFTSSNWSKSINQSNLFINGWNYGQADVKGKNIEFSWENEPIFEIPCTNVSNVIANKNEAILEFHQNEQSKVQLMEMRFHMPVDLENEEDTDKVEEFKKAVLAYAGLEAETEQPICLLTDILCTTPRGRYDIKVYPTSIALHGKTYDYKIPVKTINRLFLVPHKDGRQVYFVLSLNPPIRQGQTHYSYLIFEFGKDEEEDLELSLTDEQLDYFNGNLQREMTGPIYETISILFKSICNLKVTVPGRFLGSSGTPAIQCTHRQNLGLLYPMEKGFLFIQKPVMYIRFEEISSCHFARSDSGTVTRTFDFEIDLKTGSSLTFSAMDKEENNKLFDYLNKKEIKIRNSHRIDNKSAGYGSSDEDDIDPYKSTVKAEGREQDDDSDDESTDEDYDLDKDMKKQKNDKDSSEGSGSEPDDEYDSGSEKDASGTGESDPDEENIEPKKKESKEKKNKREKKEKPVKEKAVKKGKKTKDPNEPKRATTAYIIWFNANRNSMKEDGDTLGDVAKKAGAKWKSMSADDKKEWNDKAAQDKARYEAEMKEYKKNGGGVEKASGPSTKKSSDQSPGKQFKSKEHISDTDDSDDDEPLKAKKDESDAASESSGESD. |
For Research Use Only | Not For Clinical Use.
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