Mouse Anti-Horse CFTR Antibody (MO-AB-44031W)


Cat: MO-AB-44031W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityHorse (Equus caballus)
CloneMO44031W
SpecificityThis antibody binds to Horse CFTR.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome.
Product OverviewMouse Anti-Horse CFTR Antibody is a mouse antibody against CFTR. It can be used for CFTR detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCystic fibrosis transmembrane conductance regulator; CFTR
UniProt IDQ9TSW8
Protein RefseqThe length of the protein is48 amino acids long.
The sequence is show below: LICLARSVLSKAKILLLDEPSAHLDPITYQIIRRTLKQAFADCTVISR.
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For Research Use Only | Not For Clinical Use.
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