Mouse Anti-Nile tilapia cftr Antibody (MO-AB-32902H)
Cat: MO-AB-32902H
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Nile tilapia (Oreochromis niloticus) |
| Clone | MO32902C |
| Specificity | This antibody binds to Nile tilapia cftr. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma membrane; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. |
| Product Overview | This product is a mouse antibody against cftr. It can be used for cftr detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Cystic fibrosis transmembrane conductance regulator; EC 3.6.3.49; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel; LOC100710776 |
| UniProt ID | I3J7T8 |
| Protein Refseq | The length of the protein is 1505 amino acids long. The sequence is show below: MQKSPIEDANFFSKFFFWWVTPLLRKGFRKKLDLSDVYKAPSFDLADNLSERLEREWDREVVSATAKRKPKLLRALARCFFWPFAFFGVLLYLGEASKTVQPQISGRIIASFDPFHAPERSQGLYLSLGLCLLFTARFLLLQPAIFGLHHLGMQIRIALFSLIYKKTLKLSSRVLDKISTGQLVSLMSANLNKLDESLGLAHFIWITPLQCILCVGLVWELIEVNGFCGLAALTLMGIVQAWLSTKMAPHRANRAPITSRRLALTTEIIENIHSVKAYGWEEVMENIIKNIRQDEMTLTRKIGSLRYFYSASYFFSAIFVILSAIIPYALSKGIILRRIFTTASYFMVLRMTLTRQFPGSLQMWYDTMTLLHKIEDFLMKEEYSGLEYNLTTSELELVNVSASWDEHIGELFEKIQQESKANGHLNGDPGLFFTNLYVTPVLRNISLHLDKGQMLAVAGSTGSGKSSLLMMILGELVPTEGKIRHSGRISYSPQTSWIMPGTIRDNILFGLTYDEYRYNSVIQACQLEEDFTLLPEKDKTYLVDGGGTLSGGQRARLCLARAVYKDADLYLLDAPFTHLDIATEKEIFENCICKLMASKTRVVVTSKLEHLKRADKILLLHNGDCYFYGTFSELQAKRPDFSSLLLGLEAYDNINAERRGSILTETLRRVSVDETASFRGPEPIRQSFRHAPAQSHPLGDGYPEKRKQSLILNPLAAARKFSFIGNSQQTGNTTVEDRSDELPERRFSVVPEDEQIEEALPRSNLYHDEFQHLSGQRRQSVLEFITSARGQERREQMQSSFRKKLSITPQYNLPSDLDIYSRRLSKDSVYDISEDVDEEDMEQCFADERDKNVFETTSWNTYLRYVNTNRNLVYVLIFILIVSVMEVAGSVLGIFLITDEIWRDAANPSSPNYIDEQHPNASSTPVHLAVIMTPTSAYYIIYIFVAHADSILALGFFRGLPLVHTLLTVSKRLHEQMLSSVLRAPMSVLNTMKTARIVNRFTKDMAIIDDMLPLVLFDLIQVSLIVAGAIFTVSIIEPYIFIAALPLAFIYVFLRKYFLRTGQQLKVLEAEARTPIFSHLILSLKGLWTIRAFERQTYFETLFHKALNTHTAAWFHYLSVLRWFLFRCDMLFTVFFTAAAFIATGSNRDKPGQIGIIVALAMLICGIFQWAVITSIAVDGMMRSVNRVFKFIDLPPEDPRLGKSKGGGRGPDIVIDNPHARDYWPNRGQLDVRGLTVKYTEAGRAILNNISFSVEGGQSVGLLGRTGSGKSTLLSALLRLTHTEGDISIDGVSWNSVSLQTWRKAFGVVPQKVFILTGTFRMNLDPHGNYSDIELWKVAEEVGLKSVIEQFPDKLDFQLEYGGSVLCNGHKQLVCLARSILSRARILLLDEPSAYLDPITLKVLRKTLKQAFSGCTVIMSEHRVDPLTDCQSFLMIEGSSMKTYDSIQKLMNEKSHLKQAMSTADRLRLFPTLHRLNSNKRPPPQTAKISSLPEEAEDEVHDTRL. |
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For Research Use Only | Not For Clinical Use.
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