Rabbit Anti-HSPB8 Antibody (MO-DKB-01097W)


Cat: MO-DKB-01097W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Dog (Canis lupus familiaris), Rhesus (Macaca mulatta)
ImmunogenA synthetic peptide containing sequences within the C-terminal region of human HSP22.
EpitopeThe epitope is in the C-terminal of HSPB8.
FormatLiquid or Lyophilized
Buffer0.1M Tris, pH 7, 0.1M Glycine, 10% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified

Application Information

ApplicationWB, IF, IHC, IHC-P
Application NotesWestern Blot 1:500-1:3000
Immunocytochemistry/Immunofluorescence 1:100-1:1000
Immunohistochemistry 1:10-1:500
Immunohistochemistry-Paraffin 1:100-1:1000

Target

IntroductionThe protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Product OverviewThis product is a Rabbit antibody against the C-terminal of the HSPB8. It can be used for HSPB8 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesHeat Shock Protein Family B (Small) Member 8; Small Stress Protein-Like Protein HSP22; Heat Shock 27kDa Protein 8; Heat Shock 22kDa Protein 8; E2-Induced Gene 1 Protein; Alpha-Crystallin C Chain; Protein Kinase H11; E2IG1; HSP22;
Gene ID26353
UniProt IDQ9UJY1
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For Research Use Only | Not For Clinical Use.
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