AibGenesis™ Mouse Anti-Iap2 Antibody (CBMOAB-20892FYA)
Cat: CBMOAB-20892FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-20892FYA | Monoclonal | Fruit fly (Drosophila melanogaster), A. aegpti (Aedes aegpti), Silkworm (Bombyx mori) | WB, ELISA | MO20892FYA | 100 µg | ||
| MO-AB-05092Y | Monoclonal | A. aegpti (Aedes aegpti) | WB, ELISA | MO05092Y | 100 µg | ||
| MO-AB-69964W | Monoclonal | Silkworm (Bombyx mori) | WB, ELISA | MO69964W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster), A. aegpti (Aedes aegpti), Silkworm (Bombyx mori) |
| Clone | MO20892FYA |
| Specificity | This antibody binds to fruit fly Iap2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations; Cytosol |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Required for activation of NF-kappaB transcription factors in the immune deficiency (Imd) signaling cascade which is essential for innate immune responses upon infection by Gram-negative bacteria (PubMed:16894030, PubMed:17068333). Promotes cytoplasmic cleavage of Rel and its translocation to the nucleus where it drives expression of antimicrobial peptides (PubMed:17068333, PubMed:24374974). Binds, polyubiquitinates and activates Dredd which is required for Rel-mediated induction of antimicrobial peptides (PubMed:22549468). Anti-apoptotic protein which binds, ubiquitinates and inactivates the effector caspase Drice (PubMed:18166655). Suppresses rpr and hid-dependent cell death in the eye (PubMed:8548811). However, has also been shown to have little, if any, role in the regulation of the canonical caspase-dependent apoptosis pathway (PubMed:17068333). Plays a role in regulating the expression of ion channels (PubMed:24374974). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-D. melanogaster Iap2 Antibody is a mouse antibody against Iap2. It can be used for Iap2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Apoptosis 2 inhibitor; IAP homolog A; IAP-like protein; ILP; dILP; Inhibitor of apoptosis 2; dIAP2; Iap2; DIHA ILP |
| UniProt ID | Q24307 |
| Protein Refseq | The length of the protein is 498 amino acids long. The sequence is show below: MTELGMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSPICSMVLAPNHCGNVPRSQESDNEGNSVVDSPESCSCPDLLLEANRLVTFKDWPNPNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSQPATAPAPTLQADVLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGCAFSTLDELLHDIFDDAGAGAALEVREPPEPSAPFIEPCQATTSKAASVPIPVADSIPAKPQAAEAVANISKITDEIQKMSVATPNGNLSLEEENRQLKDARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFLS. |
For Research Use Only | Not For Clinical Use.
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