AibGenesis™ Mouse Anti-KNSTRN Antibody (CBMOAB-46578FYA)
Cat: CBMOAB-46578FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-46578FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Frog (Xenopus laevis), Zebrafish (Danio rerio) | WB, ELISA | MO46578FYA | 100 µg | ||
| CBMOAB-82208FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO82208FYA | 100 µg | ||
| MO-AB-04046W | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO04046W | 100 µg | ||
| MO-AB-04731H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO04731C | 100 µg | ||
| MO-AB-14692R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO14692R | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Frog (Xenopus laevis), Zebrafish (Danio rerio) |
| Clone | MO46578FYA |
| Specificity | This antibody binds to Rhesus KNSTRN. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase (PubMed:19667759). Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture (PubMed:19667759, PubMed:22110139). The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments (PubMed:21402792). Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division (PubMed:23035123). May be involved in UV-induced apoptosis via its interaction with PRPF19; however, these results need additional evidences (PubMed:24718257). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Rhesus KNSTRN Antibody is a mouse antibody against KNSTRN. It can be used for KNSTRN detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | KNSTRN |
| UniProt ID | F7E6L7 |
| Protein Refseq | The length of the protein is 274 amino acids long. The sequence is show below: MAAPEPPPGNRMFRTTWLSTECDSHPLPPSYRKFPFETEAANLAGGATVASGHLLKESDKDCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPASALSGGQPADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTTTRRNVRKGYKPLSKQKSEDELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQ. |
For Research Use Only | Not For Clinical Use.
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