Mouse Anti-Maize TERT Antibody (MO-AB-49701W)
Cat: MO-AB-49701W
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Maize (Zea mays) |
Clone | MO49701W |
Specificity | This antibody binds to Maize TERT. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. |
Product Overview | Mouse Anti-Maize TERT Antibody is a mouse antibody against TERT. It can be used for TERT detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Telomerase reverse transcriptase catalytic subunit; TERT |
UniProt ID | Q1EG35 |
Protein Refseq | The length of the protein is334 amino acids long. The sequence is show below: IQLSSRGGILVDQGKSCKIRKKEIQCFLSKQVKCNILKIGQNFYSQRVGIIQGNKLSPNLCSLYFGHLENSELLKSLHDNKIDSEKDVLTPRSLLMRFIDDFIFISFSKEQALNFFNRMRRGFVNYNCYMNDSKYGFNFEVANSEHCSNRIYKGDDGFSFIPWSGLLINCETLEIQADYTRYLDIHISSTITAKMHSSAKYLESKLCHYMRPKCHPIFFDSVINSPGTVRLNIYQNFLLCAMKFHCYFRSMPDPGIMKPELLHIIKRTFRYMHSLVAKRMHEAELQYDVRPVLKLRRKETMWLGLSAYLRALQKKQSRYSELLASLREEIGRCG. |
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For Research Use Only | Not For Clinical Use.
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