AibGenesis™ Mouse Anti-MAPKBP1 Antibody (MO-AB-04283W)
Cat: MO-AB-04283W
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- Product List
- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes) |
| Clone | MO04283W |
| Specificity | This antibody binds to Rhesus MAPKBP1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. (From NCBI) |
| Product Overview | Mouse Anti-Rhesus MAPKBP1 Antibody is a mouse antibody against MAPKBP1. It can be used for MAPKBP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Mitogen-activated protein kinase-binding protein 1 isoform b; MAPKBP1 |
| UniProt ID | H9FRK6 |
| Protein Refseq | The length of the protein is 1514 amino acids long. The sequence is show below: MAVEGSTITSRIKNLLRSPSIKLRRNKAGNRREDLSSKVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAERSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSGLLCEFSDRRLLDKWVELRNTDSFTTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASITEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLMDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVLAKNTKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWAQPGVELSVRSMLDLRQLETLAPSPRGPSQDSLATISSGPRKHGQQALETSLTSQNEKSPRPQASQPCSCPRIIRLLSQEEGVFAQDLEPAPVEDGIVYPEPSDSPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPRTPDQEQFLKQHFETLANGAAPGAPVQVPERSESRSISSRYLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGASPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNSDSSWAPKRVATASPLSGLQKAQSVHSLVPQERDEAGLQAPSPGPLLSREMEAQDGLGSLPLADGPPSRPHSYQNPTTSSMAKISRSISVGENLGLVAQPQAPAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRTPGEAEKPGFPLGLGKAHSTTERWACLGEGTTAKPRTECQAHPGPSSPCAQQLPVSSLLRGPENLPPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEHSRIAQLLRDTFSSVRQELEALAGAVPSSPGGSPGAVGAEQTQALLEQYSELLLRAVERRMERKL. |
For Research Use Only | Not For Clinical Use.
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