Mouse Anti-Marmoset CILP Antibody (MO-AB-53038W)


Cat: MO-AB-53038W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset
CloneMO53038W
SpecificityThis antibody binds to Marmoset CILP.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationExtracellular region or secreted

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionMajor alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
Product OverviewMouse Anti-Marmoset CILP Antibody is a mouse antibody against CILP. It can be used for CILP detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCartilage intermediate layer protein 1 preproprotein; CILP
UniProt IDU3D515
Protein RefseqThe length of the protein is 1186 amino acids long.
The sequence is show below: MVGTKAWVFSFLVLEVTSVLGIGRQTMLTQSVRRVQPGKRNPLISAKPANTLESPGEWTTWFNIDYPGGQGDYERLDAIRFYYGDRVCARPLQLEARTTDWTPAGSTGQVVHGSPREGFWCLNREQRPGRNCSNYTVRFLCPPGSLRRDTERIWSPWSAWSKCSAACGRTGVQTRTRTCLAEPMSLCSEATEEGQHCMGQDCKDCDLTCPMGQVNADCDACMCEDFMLHGVVSLPGGAPASGATVYLLTKTPKLLTQTDSNGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATVNAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPGPDKYFWYHNNTLLDPSLYKHESKLVLRNLKQDQAGEYFCKAQSDAGAMKSKIAQLIVIAPDETPCNPVPESYLIQLPHDCFQNATNSFYYDVGRCPVKTCAGQQDNGIRCRDVVQNCCGISKTEEREIQCSGYTLPTKVAKECSCQRCTETRSIVRGRVSAADNGEPMRFGHVYLGNSRVSMTGYKGTFTLHVPQDTDRLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKEPITLEATETNIIPLGEVVGEDPMAELEIPSKSFYRQNGEPYTGKVKASVTFLDPRNISTATAAQSDLNFISDEGDTFPLRTYGMFSVDFRDEITSESLNAGKVKVHLDSTQVKMPEHISTVKLWSLNPDTGLWEEEDDFKFENQRRNKREERTFLVGNMEIRERRLFNLDVPESRRCFVKVRAYRSERFLPSEQIQGVVISVINLEPRAGFSSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELQAVESFPKFNPNAIGVPQPYLNKLKYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGSLEVNVRSRNMGGTHRRTVGKLYGIRDVRSTRDRDQPNVSAACLEFKCSGMLYDQDRVDRTLVKVIPQGSCQRASVNPMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCVERQVGRQSAFQYLQSTPARPSATGTVQGRMPSRRQQRASRGGQRERGATASLRFPGVAQQPLSN.
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For Research Use Only | Not For Clinical Use.
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