Mouse Anti-Marmoset GCLC Antibody (MO-AB-55913W)


Cat: MO-AB-55913W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset
CloneMO55913W
SpecificityThis antibody binds to Marmoset GCLC.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Cytosol; Mitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionGlutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Product OverviewMouse Anti-Marmoset GCLC Antibody is a mouse antibody against GCLC. It can be used for GCLC detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGlutamate--cysteine ligase catalytic subunit isoform a; GCLC
UniProt IDF7I383
Protein RefseqThe length of the protein is 637 amino acids long.
The sequence is show below: MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEANMRKRRKEATSVLEENQAVCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEGDEASRSSKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVLQGMFYFRKDICKGGNAVVDGCGKAQNSMELAAEEYTLMSIDTIINGKEGVFPGLIPILNCYLENMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIGNHPDYKQDSVITDEMNYSLILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN.
For Research Use Only | Not For Clinical Use.
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