Mouse Anti-Marmoset MRE11 Antibody (MO-AB-59298W)
Cat: MO-AB-59298W
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Marmoset |
Clone | MO59298W |
Specificity | This antibody binds to Marmoset MRE11. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Product Overview | Mouse Anti-Marmoset MRE11 Antibody is a mouse antibody against MRE11. It can be used for MRE11 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Double-strand break repair protein MRE11A isoform 1; MRE11A |
UniProt ID | F6QPU1 |
Protein Refseq | The length of the protein is 709 amino acids long. The sequence is show below: MSHADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLNEILRLAQENEVDFILLGGDLFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHECKIAPTKNEQQLFYISQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMQKIPLHTVRQFFMEDIVLANHPDIFNPDNPKVTQAIQSFCLEKIEGMLENAERERLGNSRQPEKPLVRLRVDYSGGFEPFNVLRFSQKFVDRVANPKDVIHFFRHREQKEKTGEEINFGKLITKPSSEGTTLRVEDLVKQYFQTTEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRESRKKNTNEEDDEVREAMNRARALRSQSEESASAFSADDLMSIGLAEQMADDSDDSISGAASKARGRGRGRRGGRGQNSASRGVSQRGRAGTGLETSTRSRNSKTTVSASRNMSIIDAFKSARQQPSQNVTTKNYSEVIEVDESDMEEDFFPTTSKTDQRWSSASSNKNMSQSQVSKGVDFESSEDDDDDPFMNTSSLRRKRR. |
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For Research Use Only | Not For Clinical Use.
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