Mouse Anti-Marmoset NSMCE1 Antibody (MO-AB-60372W)


Cat: MO-AB-60372W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset
CloneMO60372W
SpecificityThis antibody binds to Marmoset NSMCE1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Nucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NSMCE3. Is involved in positive regulation of response to DNA damage stimulus.
Product OverviewMouse Anti-Marmoset NSMCE1 Antibody is a mouse antibody against NSMCE1. It can be used for NSMCE1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesNon-structural maintenance of chromosomes element 1 homolog; NSMCE1
UniProt IDU3DZ29
Protein RefseqThe length of the protein is 266 amino acids long.
The sequence is show below: MQGSARRTGVMTDVHRRFLQLLMTHGVLEEWDVKRMQKHCYKVHDRNATVDKLEDFINNINSVLESLYIEIKRGVTEDDGRPIYALVNLATTSVSKMATDFAENELDLFRKALELIIDSESGFASSTNILNLVDQLKGKKMKKKEAELVLQKFVQNKWLIEKEGEFTLHGRAILEMEQYIRETYPDSVKICNICHSLLIQGQSCETCGIRMHLPCVAKYFRSNAEPRCPHCNDYWPHEIPEVFDPEKEREPGISKSNRKSLRSRRH.
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For Research Use Only | Not For Clinical Use.
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