Mouse Anti-Marmoset TPP1 Antibody (MO-AB-66771W)


Cat: MO-AB-66771W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset
CloneMO66771W
SpecificityThis antibody binds to Marmoset TPP1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Endosome; Lysosome; Golgi apparatus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Product OverviewMouse Anti-Marmoset TPP1 Antibody is a mouse antibody against TPP1. It can be used for TPP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesTripeptidyl-peptidase 1 preproprotein; TPP1
UniProt IDF6VZ09
Protein RefseqThe length of the protein is 563 amino acids long.
The sequence is show below: MGLQACLLGLFALILSGKCSYSPEPDQQRTLPSGWVSLGRADPEEELSLTFALRQQNLERLSELVQVVSDPSSPQYGKYLTLDHVADLVRPSPLTLHTVQKWLLAAGVRNCRSVITQDFLTCWLSIRQAELLLPGAEFHHYMGGPAETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVAGTIGIHLGVTPNVIRKRYNLTAQDVGSGTSNNSQACAQFLEQYFRDSDLAEFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESTLPHVHTVSYGDDEDSLSSAYIQRVNTELMKAATRGLTLLFASGDSGAGCWSVSGRHQFRPSFPASSPYVTTVGGTSFQNPFRITNEIVDYISGGGFSNVFPRPSYQEEAVAKFLNSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNSVPIPWVSGTSASTPVFGGLLSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTHGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKSLLNP.
For Research Use Only | Not For Clinical Use.
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