Mouse Anti-Mcm4 Antibody, IgG2a kappa (MOFY-0922-FY14)


Cat: MOFY-0922-FY14
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Specifications

Host speciesMouse
Species ReactivityS. cerevisiae
CloneMC-12
ImmunogenMapping of amino acids 1-300 at the N-terminus of Saccharomyces cerevisiae-derived Mcm4
FormatLiquid or Lyophilized
BufferRefer to COA
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 95% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, IP, IF, ELISA

Target

IntroductionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Product OverviewMOFY-0922-FY14 is a mouse antibody against Mcm4. It can be used for Mcm4 detection in Western Blot, Immunoprecipitation, Immunofluorescence, ELISA.
Alternative NamesMinichromosome Maintenance Complex Component 4; CDC21 Homolog; P1-CDC21; CDC21; MCM4 Minichromosome Maintenance Deficient 4 (S. Cerevisiae); Homolog Of S. Pombe Cell Devision Cycle 21; Minichromosome Maintenance Deficient 4
For Research Use Only | Not For Clinical Use.
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