Mouse Anti-Mcm4 Antibody, IgG2a kappa (MOFY-0922-FY14)
Cat: MOFY-0922-FY14
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- Product Details
Specifications
Host species | Mouse |
Species Reactivity | S. cerevisiae |
Clone | MC-12 |
Immunogen | Mapping of amino acids 1-300 at the N-terminus of Saccharomyces cerevisiae-derived Mcm4 |
Format | Liquid or Lyophilized |
Buffer | Refer to COA |
Regulatory Status | For Research Use Only. Not For Clinical Use. |
Shipping | Gel Pack |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 95% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, IP, IF, ELISA |
Target
Introduction | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
Product Overview | MOFY-0922-FY14 is a mouse antibody against Mcm4. It can be used for Mcm4 detection in Western Blot, Immunoprecipitation, Immunofluorescence, ELISA. |
Alternative Names | Minichromosome Maintenance Complex Component 4; CDC21 Homolog; P1-CDC21; CDC21; MCM4 Minichromosome Maintenance Deficient 4 (S. Cerevisiae); Homolog Of S. Pombe Cell Devision Cycle 21; Minichromosome Maintenance Deficient 4 |
See other products for " MCM4 "
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CBMOAB-06462HCB | Mouse Anti-C. elegans MCM4 Antibody (CBMOAB-06462HCB) |
MO-AB-24718W | Mouse Anti-Chimpanzee MCM4 Antibody (MO-AB-24718W) |
MO-AB-02869Y | Mouse Anti-Chicken Mcm4 Antibody (MO-AB-02869Y) |
MO-AB-05079H | Mouse Anti-Frog Mcm4 Antibody (MO-AB-05079H) |
For Research Use Only | Not For Clinical Use.
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