Guinea pig Anti-MMP9 Antibody (MOFY-0622-FY225)


Cat: MOFY-0622-FY225
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Specifications

Host speciesGuinea pig
Species ReactivityRabbit
ImmunogenRecombinant Matrix Metalloproteinase 9 (MMP9)
FormatLiquid or Lyophilized
Buffer0.01M PBS, pH7.4, 50% glycerol
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationWB, IHC, ICC, IP
Application NotesWB: 0.5-2 µg/mL
IHC: 5-20 µg/mL
ICC: 5-20 µg/mL
The optimal dilution should be determined by the end user.

Target

IntroductionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Alternative NamesGELB; Gelatinase B; CLG4B; CLG4-B; 92 KDa Gelatinase; 92kDa Type IV Collagenase
For Research Use Only | Not For Clinical Use.
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