Mouse Anti-Mos Antibody, IgG2b kappa (MOFY-0922-FY462)


Cat: MOFY-0922-FY462
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Specifications

Host speciesMouse
Species ReactivityX. laevis
CloneMR38.1
Immunogenanti-maltose binding protein-Xenopus fusion protein
FormatLiquid or Lyophilized
BufferRefer to COA
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 95% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB

Target

IntroductionThe cellular homolog of the v-Mos oncogene was originally derived from the Moloney strain of murine sarcoma virus and has now been isolated from several species including human, mouse, chicken and Xenopus laevis. In each of these species, the c-Mos proto-oncogene locus consists of an exon encoding Mos, a serine/threonine protein involved in regulating the meiotic cell cycle of vertebrate oocytes kinase. Mos functions during oocyte maturation are thought to be exerted by stabilization or activation of maturation-promoting factor (MPF) complexes. Although the expression level of Mos in somatic cells is generally low, the expression level of Mos in germ cells is relatively high. When ectopically expressed during the G1 phase of the cell cycle, Mos can efficiently cause oncogenic transformation of somatic cells. Mos activates MAPK, probably through direct phosphorylation of MAPKK MEK-1.
Product OverviewMOFY-0922-FY462 is a mouse antibody against Mos. It can be used for Mos detection in Western Blot.
Alternative NamesMOS Proto-Oncogene, Serine/Threonine Kinase; V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog; Oocyte Maturation Factor Mos; Proto-Oncogene C-Mos; EC 2.7.11.1; Proto-Oncogene Serine/Threonine-Protein Kinase Mos
For Research Use Only | Not For Clinical Use.
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