Mouse Anti-NCL1 Antibody (CBMOAB-00114HCB)

Cat: CBMOAB-00114HCB

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Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-00114HCB	Monoclonal	C. elegans (Caenorhabditis elegans), Yeast, Zebrafish (Danio rerio)	WB, ELISA	MO00114HB		100 µg	Inquiry
Protein Refseq: The length of the protein is 851 amino acids long. The sequence is show below: METQLSVQLGLDSLLTDFGLESVMNKQQQLFANMGLSDIGAPTPSTAIPVPNAHLHPSMVAGSDPSNPVVGFGFGSPSSTTSSSPPLSNSPTIEQQQHAQLTAMMQGIMSNNNVAVSNGSGVQVASVPAVHCSGCKSNETATSFCQDCNANLCDNCTMAHKFMHCFADHRVVSLTTPGTGSSSSSTSSSSSASSTSSHQVPSLGGKQSPDSMMLGSGKRSVLCLQHRASELVFFCVSCNLAICRDCTVSDHPSGTHQYELIADVADKQMLKMEQLIADARSKHADMLDMFKQVDNKQQVLTASLHNAHAQLEETVSNLINVIQDQKKTLAKDIDNAFAAKQIQLTMVDKRIQSMADKLSQTIEFSRRLMSFASPAEVMVFKQLLDTRLQLFLGFNPDTSGVLMTPCEIEYLGAAGLFNNSASTVSQLLGSVHGGSPINNAPAANDFLMPQAGLAPIGRAQSRIIPIEQNQLARSPPHHIAGSLPMNAYSDSNLLRPNKDFGGSSQSLGPFNPLGASVPGAAADPFSSQYDKWSLGVEPSVGGLLEGGNVDEEKFQTLFPPSRSQIKRQKMIYHCKFGEFGVMEGQFTEPSGVAVNGQGDIVVADTNNHRIQVFDKEGRFKFQFGECGKRDGQLLYPNRVAVNRTTGDFVVTERSPTHQIQVYNQYGQFLRKFGANILQHPRGVCVDSKGRIIVVECKVMRVIIFDMFGNILQKFSCSRYLEFPNGVCTNDKNEILISDNRAHCIKVFSYEGQYLRQIGGEGVTNYPIGVGINSLGEVVVADNHNNFNLTVFSQDGTMIGALESRVKHAQCFDVALVDDGSVVLASKDYRLYLYRFLPATSGQSTSSASSQI.
CBMOAB-02559CR	Monoclonal	Yeast	WB, ELISA	MO02559CR		100 µg	Inquiry
Protein Refseq: The length of the protein is 684 amino acids long. The sequence is show below: MARRKNFKKGNKKTFGARDDSRAQKNWSELVKENEKWEKYYKTLALFPEDQWEEFKKTCQAPLPLTFRITGSRKHAGEVLNLFKERHLPNLTNVEFEGEKIKAPVELPWYPDHLAWQLDVPKTVIRKNEQFAKTQRFLVVENAVGNISRQEAVSMIPPIVLEVKPHHTVLDMCAAPGSKTAQLIEALHKDTDEPSGFVVANDADARRSHMLVHQLKRLNSANLMVVNHDAQFFPRIRLHGNSNNKNDVLKFDRILCDVPCSGDGTMRKNVNVWKDWNTQAGLGLHAVQLNILNRGLHLLKNNGRLVYSTCSLNPIENEAVVAEALRKWGDKIRLVNCDDKLPGLIRSKGVSKWPVYDRNLTEKTKGDEGTLDSFFSPSEEEASKFNLQNCMRVYPHQQNTGGFFITVFEKVEDSTEAATEKLSSETPALESEGPQTKKIKVEEVQKKERLPRDANEEPFVFVDPQHEALKVCWDFYGIDNIFDRNTCLVRNATGEPTRVVYTVCPALKDVIQANDDRLKIIYSGVKLFVSQRSDIECSWRIQSESLPIMKHHMKSNRIVEANLEMLKHLLIESFPNFDDIRSKNIDNDFVEKMTKLSSGCAFIDVSRNDPAKENLFLPVWKGNKCINLMVCKEDTHELLYRIFGIDANAKATPSAEEKEKEKETTESPAETTTGTSTEAPSAAN.
CBMOAB-88499FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO88499FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 572 amino acids long. The sequence is show below: MFEEAGEVLENMLKVSFPLSLVLFLVLVCPLRAEAAHEFSVYRMQQYDLQGQTYGSRNAILNTEARTVEAEVLSRRCVMMRLADFSYEKYQKALRQSAGAVVIILPHNMSTLPQDIVQQFMELEPELLATETIVPVYFALEDEELLSIYTQTQISSSSQGSSSAAEVLLHTATANGFQMVTSGAQSKAVSDWAITSLEGRLTGSGGEDLPTIVLVAHYDSFGVAPWLSYGADSNGSGVAILLELARLFSRLYSYKRTHAGYNLLFFLSGGGKFNYQGTKRWLEDNLDHTDASLLQDNVAFVLCLDTLGNSDNLHLHVSKPPKEGSPQYTLLKELETVVAHQHPDLKFAMVHKKINLADDTLAWEHERFGIRRLPAFTLSHLESHRSPARHSIMDMRSVSPSLEGAGEATTGPHVDLGKLSRNTKVIAETLARVIYNLTEKGVTGDLEIFTEQMQVQEDQLASLVDWLTAQPRAAQLLDKDSSIINTLEHQLSRYLKDVKRHLVRADKRDPEFVFYDQLKQTMNAYRVKPAIFDLLLAVCIASYLGVLYLAIQNFGLLYGFLRRVTAPRVKQH.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	C. elegans (Caenorhabditis elegans), Yeast, Zebrafish (Danio rerio)
Clone	MO00114HB
Specificity	This antibody binds to C. elegans NCL1.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Translational repressor that inhibits protein synthesis (PubMed:9508766, PubMed:26492166). Represses the translation of mRNAs such as fib-1, probably by being recruited by RNA-binding protein nos-2 and the Pumilio proteins puf-5, puf-8 and puf-9 to the consensus core PUF binding motif in the 3'-UTR of fib-1 mRNA (PubMed:26492166). Negatively regulates ribosomal RNA (rRNA) synthesis, ribosomal protein synthesis and nucleolus size (PubMed:9508766, PubMed:8582642, PubMed:22768349, PubMed:26492166, PubMed:28853436). Its role in the negative regulation of nucleolus size is most likely through its negative regulation of the translation of proteins such as the rRNA 2'-O-methyltransferase fib-1, and dao-5 (PubMed:26492166, PubMed:28853436). Might act directly as a transcription factor to inhibit RNA polymerase I (rRNA) and III (5S RNA) transcription (PubMed:9508766). Plays a role in embryonic development, and in particular, is involved in regulating the localization of proteins, such as par-2, that are required for embryonic cell polarity (PubMed:18652816). Plays a role in the regulation of lifespan, and the response to nutrient availability (PubMed:28853436).
Product Overview	Mouse Anti-C. elegans NCL1 Antibody is a mouse antibody against NCL1. It can be used for NCL1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	B-box type zinc finger protein ncl-1; ncl-1
Gene ID	176084
UniProt ID	P34611
Protein Refseq	The length of the protein is 851 amino acids long. The sequence is show below: METQLSVQLGLDSLLTDFGLESVMNKQQQLFANMGLSDIGAPTPSTAIPVPNAHLHPSMVAGSDPSNPVVGFGFGSPSSTTSSSPPLSNSPTIEQQQHAQLTAMMQGIMSNNNVAVSNGSGVQVASVPAVHCSGCKSNETATSFCQDCNANLCDNCTMAHKFMHCFADHRVVSLTTPGTGSSSSSTSSSSSASSTSSHQVPSLGGKQSPDSMMLGSGKRSVLCLQHRASELVFFCVSCNLAICRDCTVSDHPSGTHQYELIADVADKQMLKMEQLIADARSKHADMLDMFKQVDNKQQVLTASLHNAHAQLEETVSNLINVIQDQKKTLAKDIDNAFAAKQIQLTMVDKRIQSMADKLSQTIEFSRRLMSFASPAEVMVFKQLLDTRLQLFLGFNPDTSGVLMTPCEIEYLGAAGLFNNSASTVSQLLGSVHGGSPINNAPAANDFLMPQAGLAPIGRAQSRIIPIEQNQLARSPPHHIAGSLPMNAYSDSNLLRPNKDFGGSSQSLGPFNPLGASVPGAAADPFSSQYDKWSLGVEPSVGGLLEGGNVDEEKFQTLFPPSRSQIKRQKMIYHCKFGEFGVMEGQFTEPSGVAVNGQGDIVVADTNNHRIQVFDKEGRFKFQFGECGKRDGQLLYPNRVAVNRTTGDFVVTERSPTHQIQVYNQYGQFLRKFGANILQHPRGVCVDSKGRIIVVECKVMRVIIFDMFGNILQKFSCSRYLEFPNGVCTNDKNEILISDNRAHCIKVFSYEGQYLRQIGGEGVTNYPIGVGINSLGEVVVADNHNNFNLTVFSQDGTMIGALESRVKHAQCFDVALVDDGSVVLASKDYRLYLYRFLPATSGQSTSSASSQI.

For Research Use Only | Not For Clinical Use.

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