Mouse Anti-Nile tilapia pgk1 Antibody (MO-AB-33596H)
Cat: MO-AB-33596H
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Nile tilapia (Oreochromis niloticus) |
| Clone | MO33596C |
| Specificity | This antibody binds to Nile tilapia pgk1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. |
| Product Overview | This product is a mouse antibody against pgk1. It can be used for pgk1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Phosphoglycerate kinase; EC 2.7.2.3; LOC100701118 |
| UniProt ID | I3KL67 |
| Protein Refseq | The length of the protein is 417 amino acids long. The sequence is show below: MSLSNKLTLDKVDVKGKRVVMRVDFNVPMKDKAITNNQRIKAALPSIQHCLDHGAKSVVLMSHLGRPDGNVMPEKYSLEPVAAELKTLLGRDVTFLKDCVGPEVEAACADPASGSIILLENLRFHVAEEGKGKDPSGNKTKATQEQIDSFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAAGFLMKKELDYFAMALEKPQRPFLAILGGAKVKDKIQLINNMLDKVDEMIIGGGMAFTFLKVLNNMEIGTSLYDEEGAGIVKDLMAKAEKNKVKITLPVDFVTADKFDEHAATGTATVAAGIPAGWMGLDCGPESSKAYAEAVGRAKQIVWNGPVGVFEWENFAKGTKNLMDKVVEVTKSGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSSA. |
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For Research Use Only | Not For Clinical Use.
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