Rabbit Anti-PGK1 Antibody (MO-DKB-01211W)


Cat: MO-DKB-01211W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Bovine (Bos taurus), Primat, Rhesus (Macaca mulatta), Sheep (Ovis aries)
ImmunogenRecombinant protein containing sequences in the central region of human PGK1.
EpitopeThe epitope is in the Center of PGK1.
FormatLiquid or Lyophilized
BufferPBS, pH 7, 20% Glycerol, 1% BSA
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified
Cellular LocalizationCytoplasm

Application Information

ApplicationWB, IHC-P
Application NotesWestern Blot 1:500-1:3000

Target

IntroductionThe protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
Product OverviewThis product is a Rabbit antibody against the Center of the PGK1. It can be used for PGK1 detection in Western Blot, Immunohistochemistry-Paraffin.
Alternative NamesPhosphoglycerate Kinase 1; Cell Migration-Inducing Gene 10 Protein; Primer Recognition Protein 2; EC 2.7.2.3; PRP 2; PGKA; Epididymis Secretory Sperm Binding Protein Li 68p; HEL-S-68p; MIG10;
Gene ID5230
UniProt IDP00558
For Research Use Only | Not For Clinical Use.
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