AibGenesis™ Mouse Anti-NOP1 Antibody (CBMOAB-02620CR)
Cat: CBMOAB-02620CR
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-02620CR | Monoclonal | Yeast, C. elegans (Caenorhabditis elegans) | WB, ELISA | MO02620CR | 100 µg | ||
| CBMOAB-07641HCB | Monoclonal | C. elegans (Caenorhabditis elegans) | WB, ELISA | MO07641HB | 100 µg | ||
| MO-DKB-03766W | Monoclonal | Yeast | IF, WB | ms2109-059 | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Yeast, C. elegans (Caenorhabditis elegans) |
| Clone | MO02620CR |
| Specificity | This antibody binds to Yeast NOP1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (PubMed:2686980, PubMed:1825809, PubMed:12215523). Site specificity is provided by a guide RNA that base pairs with the substrate (PubMed:2686980, PubMed:1825809). Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (PubMed:2686980, PubMed:1825809). Involved in the biogenesis of the 18S rRNA (PubMed:2686980, PubMed:1825809). Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Yeast NOP1 Antibody is a mouse antibody against NOP1. It can be used for NOP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | rRNA 2'-O-methyltransferase fibrillarin; EC 2.1.1; Histone-glutamine methyltransferase; U3 small nucleolar RNA-associated protein NOP1; Nucleolar protein 1; U3 snoRNA-associated protein NOP1; NOP1; LOT3; YDL014W |
| UniProt ID | P15646 |
| Protein Refseq | The length of the protein is 327 amino acids long. The sequence is show below: MSFRPGSRGGSRGGSRGGFGGRGGSRGGARGGSRGGFGGRGGSRGGARGGSRGGFGGRGGSRGGARGGSRGGRGGAAGGARGGAKVVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSGLKK. |
For Research Use Only | Not For Clinical Use.
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