Mouse Anti-NPR1 Antibody (MO-AB-32222W)


Cat: MO-AB-32222W
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  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-AB-32222W Monoclonal Dog (Canis lupus familiaris), A. thaliana (Arabidopsis thaliana), Arabidopsis, C. elegans (Caenorhabditis elegans), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Elephant (Loxodonta africana), French-bean, Frog (Xenopus laevis), Guinea pig (Cavia porcellus), Horse (Equus caballus), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta), Sheep (Ovis aries), Yeast WB, ELISA MO32222W 100 µg
CBMOAB-52913FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO52913FYA 100 µg
CBMOAB-02645CR Monoclonal Yeast WB, ELISA MO02645CR 100 µg
CBMOAB-07696HCB Monoclonal C. elegans (Caenorhabditis elegans) WB, ELISA MO07696HB 100 µg
MO-AB-08689W Monoclonal Cat (Felis catus) WB, ELISA MO08689W 100 µg
MO-AB-21481W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO21481W 100 µg
MO-AB-36325W Monoclonal French-bean WB, ELISA MO36325W 100 µg
MO-AB-42161W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO42161W 100 µg
MO-AB-45807W Monoclonal Horse (Equus caballus) WB, ELISA MO45807W 100 µg
MO-AB-60266W Monoclonal Marmoset WB, ELISA MO60266W 100 µg
MO-AB-16887R Monoclonal Cattle (Bos taurus) WB, ELISA MO16887R 100 µg
MO-AB-27814R Monoclonal Pig (Sus scrofa) WB, ELISA MO27814R 100 µg
MO-AB-05733H Monoclonal Frog (Xenopus laevis) WB, ELISA MO05733C 100 µg
MO-AB-33498H Monoclonal Nile tilapia (Oreochromis niloticus) WB, ELISA MO33498C 100 µg
MO-AB-00912L Monoclonal Elephant (Loxodonta africana) WB, ELISA MO00912L 100 µg
MO-AB-03206Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO03206Y 100 µg
MO-AB-08981Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO08981Y 100 µg
MO-AB-16356Y Monoclonal Sheep (Ovis aries) WB, ELISA MO16356Y 100 µg
MO-DKB-04071W Polyclonal A. thaliana (Arabidopsis thaliana) WB 100 µg
MOFAB-616W Monoclonal Arabidopsis WB, IHC 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityDog (Canis lupus familiaris), A. thaliana (Arabidopsis thaliana), Arabidopsis, C. elegans (Caenorhabditis elegans), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Elephant (Loxodonta africana), French-bean, Frog (Xenopus laevis), Guinea pig (Cavia porcellus), Horse (Equus caballus), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta), Sheep (Ovis aries), Yeast
CloneMO32222W
SpecificityThis antibody binds to Dog NPR1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionGuanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).
Product OverviewMouse Anti-Dog NPR1 Antibody is a mouse antibody against NPR1. It can be used for NPR1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGuanylate cyclase; EC 4.6.1.2; NPR1
UniProt IDF1PMP1
Protein RefseqThe length of the protein is 1060 amino acids long.
The sequence is show below: MLRPGRPAGALPLPPPPPPLLLLLLLPGSQAGNLTVAVVLPLANTSYPWSWARVGPAVELALAAVRAQPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGAKDEYALTTRAGPSHAKLGDLVAALHRRLGWERRALVLYAYRPGDDQPCFFVVEGLYVRVRERLNITVDHLEFAEGDLDQYALLLHTVRRQGRVIYICSSPDAFRTLMLLAMEAGLSGEDYVFFHLDLFGHSLQGAPGLAPHRPWERGDGQDVSAHQAFQAAKIITYKEPENPEYLEFLQQLKHLAHEQFNFTVEDGLVNTIPASFHDGLLLYVQAVTETLAHGGAVTDGEAITQRMRNRSFQGVTGYLKMDSNGDRETDFSLWDMHPETGTFRVVLNYNGTSQELVAVPGRKLSWPLGYPPPDIPKCGFDNEDPACSQDHFSTLEVLALVGSLSLLSILTVSFFIYRKMQLEKELASELWRVRWEDVQPSSLERHLRSTGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENEGITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDFGLESFRDPEPEQGHILYAKKLWTAPELLRMASPPARGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIVERVTRGEQPPFRPSLALQSHLEELGQLMQRCWAEEPQERPPFQQIRLMLRKFNRESSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRRAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAQSTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGLLHAREVARMALALLDAVRSFRIRHRPQEELRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG.
For Research Use Only | Not For Clinical Use.
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