Mouse Anti-O. mykiss SUMO2 Antibody (MO-AB-13358Y)
Cat: MO-AB-13358Y
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | O. mykiss (Oncorhynchus mykiss) |
| Clone | MO13358Y |
| Specificity | This antibody binds to O. mykiss SUMO2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. Plays a role in the regulation of sumoylation status of SETX (By similarity). |
| Product Overview | This product is a mouse antibody against SUMO2. It can be used for SUMO2 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Small ubiquitin-related modifier; SUMO; SUMO2 |
| UniProt ID | C1BGK2 |
| Protein Refseq | The length of the protein is 95 amino acids long. The sequence is show below: MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLTIRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGLY. |
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For Research Use Only | Not For Clinical Use.
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