Mouse Anti-PARN Antibody (CBMOAB-38136FYC)


Cat: CBMOAB-38136FYC
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-38136FYC Monoclonal A. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rhesus (Macaca mulatta), Zebrafish (Danio rerio) WB, ELISA MO38136FC 100 µg
CBMOAB-53896FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO53896FYA 100 µg
CBMOAB-91446FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO91446FYA 100 µg
MO-AB-16132W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO16132W 100 µg
MO-AB-17562R Monoclonal Cattle (Bos taurus) WB, ELISA MO17562R 100 µg
MO-AB-61015W Monoclonal Marmoset WB, ELISA MO61015W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
CloneMO38136FC
SpecificityThis antibody binds to Arabidopsis PARN.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Mitochondrion; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product OverviewMouse Anti-Arabidopsis PARN Antibody is a mouse antibody against PARN. It can be used for PARN detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesPoly(A)-Specific Ribonuclease; Deadenylation Nuclease; Polyadenylate-Specific Ribonuclease; Deadenylating Nuclease; EC 3.1.13.4; DAN
UniProt IDQ9LG26
Protein RefseqThe length of the protein is 689 amino acids long. The sequence is show below: MRRHKRWPLRSLVCSFSSSAAETVTTSTAASATAAFPLKHVTRSNFETTLNDLRSLVKAADFVAIDLEMTGVTSAPWRDSLEFDRYDVRYLKVKDSAEKFAVVQFGVCPFRWDSRTQSFVSYPHNFFVFPRQELTFDPPAHEFLCQTTSMDFLAKYQFDFNTCIHEGISYLSRREEEEASKRLKMLHGEDGIDSSGETEELKLVRLADVLFAARMEKLLNEWRSGLLHGGNASSEFPRISNGSNQSMETVFHHMRPALSLKGFTSHQLRVLNSVLRKHFGDLVYIHSNDKSSSSRDIVVYTDSDSDKENLMKEAKDERKRLAERKIQSAIGFRQVIDLLASEKKLIVGHNCFLDIAHVYSKFVGPLPSTAEKFVASINSHFPYIVDTKILLNVNPMLHQRMKKSSTSLSSAFSSLCPQIEFSSRSSDSFLQQRVNIDVEIDNVRCSNWNAGGKHEAGYDAFMTGCIFAQACNHLGFDFKQHSQLDDFAQNEKLEKYINRLYLSWTRGDIIDLRTGHSNADNWRVSKFKYENIVLIWNFPRKLKARGIKECICKAFGSASVTSVYHVDDSAVFVLFKNSELVWDFLALKRQLESSDGPVSVLHPLSKILEGGNTGAADYEAYKEICSSHVSEVMFSDQAETVGVKSRTRPNAQCETETREENTVTVTHKASDLIDAFLANRVEVETATSN.
For Research Use Only | Not For Clinical Use.
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