Mouse Anti-Pig CIAPIN1 Antibody (MO-AB-24610R)


Cat: MO-AB-24610R
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityPig (Sus scrofa)
CloneMO24610R
SpecificityThis antibody binds to Pig CIAPIN1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations; Mitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 or CASP families. Expression of CIAPIN1 is dependent on growth factor stimulation. Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
Product OverviewThis product is a mouse antibody against CIAPIN1. It can be used for CIAPIN1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAnamorsin; Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog; CIAPIN1
UniProt IDI3L704
Protein RefseqThe length of the protein is 313 amino acids long.
The sequence is show below: MAEMADFGISAGQSVAVVWDKSSPVEALKDLVDKLQALTGDKGRVSVENINQLLQSAHKESSFDVVLSGVIPGSTTAHSAEILAEMARILRPGGCLFLKEPVETAVVNNSKVKTASKLCSALTLSGLVEVKELQRESLSPEETGSVQEHLGYRSDSLLFVRITGRKPNFEVGSSSQLKLPVAKKSSGKPAVDPAAAKLWTLSANDMEDESVDLIDSDELLDPEDLKKPDPASLRAAPCGEGKKRKACKNCTCGLAEELEKEKSRDQMSSQPKSACGNCYLGDAFRCASCPYLGMPAFKPGEKVLLSNSNLNDA.
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For Research Use Only | Not For Clinical Use.
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