AibGenesis™ Mouse Anti-POL3 Antibody (CBMOAB-03047CR)


Cat: CBMOAB-03047CR

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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-03047CR Monoclonal Yeast, Frog (Xenopus laevis) WB, ELISA MO03047CR 100 µg
MO-AB-06378H Monoclonal Frog (Xenopus laevis) WB, ELISA MO06378C 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast, Frog (Xenopus laevis)
CloneMO03047CR
SpecificityThis antibody binds to Yeast POL3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Nucleus; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCatalytic component of DNA polymerase delta (DNA polymerase III) which participates in chromosomal DNA replication (PubMed:2670563, PubMed:22119860, PubMed:31488849). Required during synthesis of the lagging DNA strands at the replication fork, binds at/or near replication origins and moves along DNA with the replication fork (PubMed:31488849). Participates in leading strand synthesis during replication initiation and termination (PubMed:31488849). Has 3'-5' proofreading exonuclease activity that corrects errors arising during DNA replication (PubMed:1648480). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-Yeast POL3 Antibody is a mouse antibody against POL3. It can be used for POL3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesDNA polymerase delta catalytic subunit; EC 2.7.7.7; DNA polymerase III; POL3; CDC2 TEX1; YDL102W
UniProt IDP15436
Protein RefseqThe length of the protein is 1097 amino acids long. The sequence is show below: MSEKRSLPMVDVKIDDEDTPQLEKKIKRQSIDHGVGSEPVSTIEIIPSDSFRKYNSQGFKAKDTDLMGTQLESTFEQELSQMEHDMADQEEHDLSSFERKKLPTDFDPSLYDISFQQIDAEQSVLNGIKDENTSTVVRFFGVTSEGHSVLCNVTGFKNYLYVPAPNSSDANDQEQINKFVHYLNETFDHAIDSIEVVSKQSIWGYSGDTKLPFWKIYVTYPHMVNKLRTAFERGHLSFNSWFSNGTTTYDNIAYTLRLMVDCGIVGMSWITLPKGKYSMIEPNNRVSSCQLEVSINYRNLIAHPAEGDWSHTAPLRIMSFDIECAGRIGVFPEPEYDPVIQIANVVSIAGAKKPFIRNVFTLNTCSPITGSMIFSHATEEEMLSNWRNFIIKVDPDVIIGYNTTNFDIPYLLNRAKALKVNDFPYFGRLKTVKQEIKESVFSSKAYGTRETKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQKEDVHYSIISDLQNGDSETRRRLAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSYLLARGQQIKVVSQLFRKCLEIDTVIPNMQSQASDDQYEGATVIEPIRGYYDVPIATLDFNSLYPSIMMAHNLCYTTLCNKATVERLNLKIDEDYVITPNGDYFVTTKRRRGILPIILDELISARKRAKKDLRDEKDPFKRDVLNGRQLALKISANSVYGFTGATVGKLPCLAISSSVTAYGRTMILKTKTAVQEKYCIKNGYKHDAVVVYGDTDSVMVKFGTTDLKEAMDLGTEAAKYVSTLFKHPINLEFEKAYFPYLLINKKRYAGLFWTNPDKFDKLDQKGLASVRRDSCSLVSIVMNKVLKKILIERNVDGALAFVRETINDILHNRVDISKLIISKTLAPNYTNPQPHAVLAERMKRREGVGPNVGDRVDYVIIGGNDKLYNRAEDPLFVLENNIQVDSRYYLTNQLQNPIISIVAPIIGDKQANGMFVVKSIKINTGSQKGGLMSFIKKVEACKSCKGPLRKGEGPLCSNCLARSGELYIKALYDVRDLEEKYSRLWTQCQRCAGNLHSEVLCSNKNCDIFYMRVKVKKELQEKVEQLSKW.
For Research Use Only | Not For Clinical Use.
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