Mouse Anti-Rabbit RAD50 Antibody (MO-AB-09634Y)
Cat: MO-AB-09634Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rabbit (Oryctolagus cuniculus) |
Clone | MO09634Y |
Specificity | This antibody binds to Rabbit RAD50. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder. |
Product Overview | This product is a mouse antibody against RAD50. It can be used for RAD50 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | RAD50 homolog isoform 1; RAD50 |
UniProt ID | B7NZL1 |
Protein Refseq | The length of the protein is 1312 amino acids long. The sequence is show below: MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPGTKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSMVCSQKSKKTEFKTLEGVITRTKHGEKVSLSSKCAEIDREMISALGVSKSVLNNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVKECQTELKYLKQNKEKACEIRDQITSKESQLTSSKEIVKSYENDLEPLKNRLKEIEHSLSKIMRLDNEIKALDSRKKQMQKDNSELEQKMEKVFQGTDDQLNDLYHNHQRTVREKERRLIDCQRELEKLNKESRLLNQEKSELLIEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFNERQIKNFHKLVRERQEREAETANQLMNDFAEKETLKQKQIDEIRDKKAGLGRIIELKSEILSRKQSELKNVKYELQQLEGSSDRILELDQELKKAERELSKAEKNSNVETLKTEVISLQNEKADLDRSLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASAEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIVDLKEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTANELKSEKLQISTNLQRRQQLEEQTVDLSTEVQSLLREIKDAKEQVNPLETALEKFQQEKEELISKKHASNKIAQDKLNDIKEKVKNIHGYVKDIENYIQDGKDDYKKQKETELNKVTAQLSECEKHKETINKEMGIMRQDIDTQKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKNEQQKLQENIENIKRNHSLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGILALDEPTTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRIKKNIDQCSEIVRCNMNSLGSYVH. |
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For Research Use Only | Not For Clinical Use.
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