Mouse Anti-Rabbit STAT3 Antibody (MO-AB-10114Y)


Cat: MO-AB-10114Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRabbit (Oryctolagus cuniculus)
CloneMO10114Y
SpecificityThis antibody binds to Rabbit STAT3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Cytosol; Nucleus; Plasma membrane

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionSignal transducer and activator of transcription that mediates cellular responses to interleukins, KITLG/SCF, and other growth factors. Mediates cellular responses to activated FGFR1, FGFR2, FGFR3, and FGFR4. Promoters with various acute phase protein genes. Activated by IL31 via IL31RA. Cytoplasmic STAT3 inhibits macroautophagy by inhibiting EIF2AK2/PKR activity. The lectin REG3G plays an important role in host defense against methicillin-resistant Staphylococcus aureus pulmonary infection by regulating the expression of antimicrobials.
Product OverviewThis product is a mouse antibody against STAT3. It can be used for STAT3 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesSignal transducer and activator of transcription; STAT3
UniProt IDG1T0H3
Protein RefseqThe length of the protein is 770 amino acids long. The sequence is show below: MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGDGAEPSAGGQFESLTFDMELTSECATSPM.
For Research Use Only | Not For Clinical Use.
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