Rabbit Anti-RAE1 (C-terminal) Antibody (Cat MO-DKB-03387W)


Cat: MO-DKB-03387W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Chicken (Gallus gallus), Primate, Frog (Xenopus), Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Human RAE1 and has cross reactivity with Mouse, Rat, Pig, Cattle, Chicken, Primate, Frog, Zebrafish RAE1.
ImmunogenThe carrier protein is coupled to a synthetic peptide containing the sequence in the C-terminal region of human RAE1.
EpitopeC-terminal
FormatLiquid or Lyophilized
BufferPBS, pH 7, 10% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified
Cellular LocalizationCytoplasm, Nucleus

Application Information

ApplicationWB, IF
Application NotesWestern Blot: 1:500-1:3000
Immunocytochemistry/Immunofluorescence: 1:100-1:1000
The optimal dilution should be determined by the end user.

Target

IntroductionMutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Product OverviewThis product is a Rabbit antibody against the RAE1. It can be used for RAE1 detection in Western Blot, Immunofluorescence.
Alternative NamesmRNA export factor; rae
UniProt IDE9QDX7
For Research Use Only | Not For Clinical Use.
Online Inquiry