Rabbit Anti-RELA Antibody (AA 490-540)


Cat: MO-NAB-00404W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Zebrafish (Danio rerio)
CloneNW0329
SpecificityThis antibody is binds to Human RELA and has cross reactivity with Mouse, Zebrafish.
ImmunogenSynthetic peptides within human NF-kB p65 aa 490-540.
EpitopeThe epitope is in the AA 490-540 of RELA.
FormatLiquid or Lyophilized
BufferTBS, pH7.4, 1% BSA, 40% Glycerol.
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A purified
Cellular LocalizationNucleus; Cytoplasm

Application Information

ApplicationWB, FC, IF, IHC, IHC-P, IP
Application NotesWestern Blot: 1:500-1:2000
Flow Cytometry: 1:50-1:100
Immunofluorescence: 1:50-1:200
Immunohistochemistry-Paraffin: 1:50-1:200

Target

IntroductionNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Product OverviewThis product is a Rabbit antibody against the AA 490-540 of the RELA. It can be used for RELA detection in Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation.
Alternative NamesRELA Proto-Oncogene, NF-KB Subunit; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3; V-Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; Nuclear Factor NF-Kappa-B P65 Subunit; NFKB3; V-Rel Reticuloendotheliosis Viral Oncogene Homolog A
Gene ID5970(Human); 19697(Mouse)
UniProt IDQ04206(Human); Q04207(Mouse)
For Research Use Only | Not For Clinical Use.
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