Mouse Anti-Rhesus CD47 Antibody (CBMOAB-38723FYA)


Cat: CBMOAB-38723FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO38723FYA
SpecificityThis antibody binds to Rhesus CD47.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCD47 is part of the rhesus (Rh) subcomplex in a band 3-based multiprotein complex. It is greatly reduced in patients with regulatory Rhnull. It is also decreased secondary in hereditary spherocytosis associated with protein 4.2 or band 3 deletions.
Product OverviewMouse Anti-Rhesus CD47 Antibody is a mouse antibody against CD47. It can be used for CD47 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCD47
UniProt IDF7F5Y9
Protein RefseqThe length of the protein is 323 amino acids long.
The sequence is show below: MWPLVAALLLGSACCGSAQLLFNKTKSVEFTFCNDTVVIPCFVTNMEAQNTTEVYVKWKFKGRDIYTFDGALNKSTAPANFSSAKIEVSQLLKGDASLKMDKSDAVSHTGNYTCEVTELTREGETIIELKYRVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGGMDEKTIALLVAGLMITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHYYVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLGLVYMKFVASNQKTIQPPRVMSHQIKRTFKESKGMMNDG.

Reference

Reference1. Deuse, T., Hu, X., Agbor-Enoh, S., Jang, M. K., Alawi, M., Saygi, C., ... & Schrepfer, S. (2021). The SIRPα-CD47 immune checkpoint in NK cells. Journal of Experimental Medicine, 218(3).
2. Cooper, D., Lindberg, F. P., Gamble, J. R., Brown, E. J., & Vadas, M. A. (1995). Transendothelial migration of neutrophils involves integrin-associated protein (CD47). Proceedings of the National Academy of Sciences, 92(9), 3978-3982.
3. Jeremy, K. P., Plummer, Z. E., Head, D. J., Madgett, T. E., Sanders, K. L., Wallington, A., ... & Avent, N. D. (2009). 4.1 R-deficient human red blood cells have altered phosphatidylserine exposure pathways and are deficient in CD44 and CD47 glycoproteins. haematologica, 94(10), 1354.
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For Research Use Only | Not For Clinical Use.
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