Mouse Anti-Rhesus CFB Antibody (CBMOAB-39088FYA)
Cat: CBMOAB-39088FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta) |
| Clone | MO39088FYA |
| Specificity | This antibody binds to Rhesus CFB. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Extracellular region or secreted |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. |
| Product Overview | Mouse Anti-Rhesus CFB Antibody is a mouse antibody against CFB. It can be used for CFB detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Complement factor B preproprotein; CFB |
| UniProt ID | H9ZC51 |
| Protein Refseq | The length of the protein is 763 amino acids long. The sequence is show below: MGSSLSPQLYLMPFILGLLSGGVTTTPLSSAQPQGSCSLEGVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLQTQDRKTVKKAECRAIRCPRPQDFENGEYRPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSRYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGHSPGEQQKRRIILDPSGSMNIYLVLDGSDSIGAGNFTGAKKCLVNLIEKVASYGVKPRYALVTYATYPRIWVKVSDQESSNADWVTKKLSEINYEDHKLKSGTNTKRALQAVYSMMSWPEDIPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPREDYLDVYVFGVGPLVDQVNINALASKKDNEQHVFKVKDMENLEDVFFQMIDESQSLSLCGMVWEHSKGTDYHKQPWQAKISVTRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGKKRDLEIEKVLFHPDYNISGKKEAGIPEFYDYDVALIKLKNKLNYDPTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQKRQKQVPAHARDFHVNLFQVLPWLKEKLQDEDLGFL. |
See other products for " cfb "
| MO-AB-02357H | Mouse Anti-Frog cfb Antibody (MO-AB-02357H) |
| MO-AB-18370W | Mouse Anti-Chimpanzee CFB Antibody (MO-AB-18370W) |
| MO-AB-24564R | Mouse Anti-Pig CFB Antibody (MO-AB-24564R) |
| CBMOAB-70195FYA | Mouse Anti-Zebrafish cfb Antibody (CBMOAB-70195FYA) |
| MO-AB-10107R | Mouse Anti-Cattle CFB Antibody (MO-AB-10107R) |
| MO-AB-14535Y | Mouse Anti-Sheep CFB Antibody (MO-AB-14535Y) |
For Research Use Only | Not For Clinical Use.
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